A semisynthetic ergot derivative that slows dopamine turnover, inhibits prolactin secretion and release of prolactin by thyrotropin-releasing hormone, and retards tumor growth and hence is used in the treatment of hyperprolactinemia associated with various pituitary tumors; an agonist at dopamine receptors also used in Parkinson disease.
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bro·mo·crip·tine .brō-mō-'krip-.tēn n a polypeptide alkaloid C32H40BrN5O5 that is a derivative of ergot and mimics the activity of dopamine in selectively inhibiting prolactin secretion
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n.
a dopamine receptor agonist, derived from ergot, that is used in the treatment of parkinsonism. It is also used to prevent lactation and to treat disorders associated with excessive secretion of prolactin (such as prolactinoma), since it inhibits the secretion of this hormone by the pituitary gland, and to treat acromegaly, as it suppresses the release of growth hormone. The drug is administered by mouth. Fairly common side-effects are dizziness and confusion. Trade name: Parlodel.
Medical dictionary. 2011.