See collagen disease.
- reactive perforating c. a rare skin disorder characterized by extrusion of collagen fibers through the epidermis; usually begins in infancy or childhood and appears clinically as recurrent umbilicated papules that resolve spontaneously. The condition may be inherited or acquired; the latter is associated with diabetes and renal insufficiency and differs from Kyrle disease in that follicular involvement is absent.
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col·la·gen·o·sis (kol″ə-jĕ-noґsis) collagen disease.Medical dictionary. 2011.