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- cold knife c. obtaining a cone of endocervical tissue with a cold knife blade so as to preserve histological characteristics and avoid desiccating tissue.
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con·iza·tion .kō-nə-'zā-shən, .kän-ə- n the electrosurgical excision of a cone of tissue from a diseased uterine cervix
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n.
surgical removal of a cone of tissue. The technique is commonly used in excising a portion of the cervix (neck) of the uterus (see cone biopsy) for the treatment of cervicitis or early cancer (carcinoma in situ).
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con·iza·tion (kon″ĭ-zaґshən) the removal of a cone of tissue, as in biopsy of the cervix uteri. Called also cone biopsy.Medical dictionary. 2011.