To substitute one thing for another, or the act of such substitution.
- sister chromatid e. the e. during mitosis of homologous genetic material between sister chromatids; increased as a result of inordinate chromosomal fragility due to genetic or environmental factors. See recombination.
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ex·change (eks-chānjґ) 1. the substitution of one thing for another. 2. to substitute one thing for another.Medical dictionary. 2011.