Analogous to adenylate (adenylyl) cyclase, but cyclizing guanosine 5′-triphosphate to guanosine 3′:5′-cyclic monophosphate and also producing pyrophosphate; activated by nitric oxide. SYN: guanyl cyclase, guanylyl cyclase.
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gua·nyl·ate cyclase 'gwän-əl-.āt- n an enzyme that catalyzes the formation of cyclic GMP from GTP
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gua·nyl·ate cy·clase (gwahґnə-lāt siґklās) [EC 4.6.1.2] an enzyme of the lyase class that catalyzes the cyclization of guanosine triphosphate to form cyclic guanosine monophosphate and pyrophosphate.Medical dictionary. 2011.