Abnormally large size of the mouth resulting from failure of fusion between the maxillary and mandibular processes of the embryonic face. [macro- + G. stoma, mouth]
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mac·ro·sto·mia .mak-rə-'stō-mē-ə n
1) the condition of having an abnormally large mouth
2) an abnormally large mouth
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mac·ro·sto·mia (mak″ro-stoґme-ə) [macro- + stom- + -ia] greatly exaggerated width of the mouth, resulting from failure of union of the maxillary and mandibular prominences, with extension of the oral orifice toward the ear. The defect may be unilateral or bilateral. See also lateral facial cleft and oblique facial cleft, under cleft.Medical dictionary. 2011.