Extract of postmenopausal urine containing primarily the follicle-stimulating hormone. SEE ALSO: human menopausal gonadotropin, urofollitropin.
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meno·tro·pins (menґo-tro″pinz) [USP] an extract of human postmenopausal urine containing both follicle-stimulating hormone and luteinizing hormone. In females, it has the property of stimulating growth and maturation of ovarian follicles. In males, it has the properties of maintaining and stimulating testicular Leydig cells related to testosterone production and of being responsible for full development and maturation of spermatozoa in the seminiferous tubules. It is used to treat male hypogonadism, to induce ovulation and pregnancy in anovulatory women in whom the anovulation is not due to primary ovarian failure, and to increase the numbers of oocytes for patients attempting conception using assisted reproductive technologies such as gamete intrafallopian transfer (GIFT) or in vitro fertilization; administered intramuscularly. Called also human menopausal gonadotropin.Medical dictionary. 2011.