- toxic epidermal n. (TEN) a syndrome in which a large portion of the skin becomes intensely erythematous with epidermal necrosis, and peels off in the manner of a second-degree burn, often simultaneous with the formation of flaccid bullae, resulting from drug sensitivity or of unknown cause; the level of separation is subepidermal, unlike staphylococcal scalded skin syndrome in which there is subcorneal change. SYN: Lyell syndrome.
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ne·crol·y·sis (nə-krolґĭ-sis) [necro- + -lysis] separation or exfoliation of tissue due to necrosis.Medical dictionary. 2011.