Akademik

Amplification
Making multiple copies of a gene or of any sequence of DNA. Repeated copying of a piece of DNA. In amplification there is an increase in the number of copies of any particular piece of DNA. Gene amplification plays a role in cancer cells. A tumor cell amplifies, or copies, DNA segments as a result of cell signals and sometimes environmental events. Amplification can occur in vivo (in the living individual) or in vitro (literally "in glass", or in a plastic vessel in the laboratory).
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The process of making larger, as in increasing an auditory or visual stimulus to enhance its perception. [L. amplificatio, an enlarging]
- genetic a. a process for producing an increase in pertinent genetic material, particularly for increasing the proportion of plasmid DNA to that of bacterial DNA. Includes the production of extrachromosomal copies of the genes for RNA. This process is usually seen in malignant cells in humans.
- linear a. a hearing aid circuit in which all frequencies receive equivalent a..

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am·pli·fi·ca·tion .am-plə-fə-'kā-shən n
1) an act, example, or product of amplifying
2) a usu. massive replication of genetic material and esp. of a gene or DNA sequence (as in a polymerase chain reaction)

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am·pli·fi·ca·tion (am″plĭ-fĭ-kaґshən) [L. amplificatio] the act or result of increasing in number, size, power, or other variable, such as the increase of an auditory or visual stimulus as a means of improving its perception.

Medical dictionary. 2011.