To pierce; to pass into the deeper tissues or into a cavity.
* * *
1) to pass into or through <enzymes that help the sperm \penetrate the zona pellucida (Anna Maria Gillis)>
2) to insert the penis into the vagina of in copulation vi to pass, extend, pierce, or diffuse into or through something <penetrating percutaneous nephroscopy or ureteroscopy (R. A. Riehle )(et al)>
Medical dictionary. 2011.