A plasma glycoprotein that in complex with kininogen serves as a cofactor in the activation of factor XII. P. also serves as the proenzyme for plasma kallikrein. SYN: Fletcher factor.
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pre·kal·li·kre·in (pre″kal-ĭ-kreґin) a plasma protein that is the proenzyme of plasma kallikrein, being cleaved and activated by activated coagulation factor XII.Medical dictionary. 2011.