platelet-derived growth factor n a mitogenic growth factor that is found esp. in platelets, consists of two polypeptide chains linked by bonds containing two sulfur atoms each, stimulates cell proliferation (as in connective tissue, smooth muscle, and glia), and plays a role in wound healing abbr. PDGF
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a substance found in the alpha granules of platelets, capable of inducing proliferation of vascular endothelial cells, vascular smooth muscle cells, fibroblasts, and glia cells; its action contributes to the repair of damaged vascular walls.Medical dictionary. 2011.