si·bu·tra·mine sə-'byü-trə-.mēn, -mən n an appetite suppressant that is administered orally in the form of its hydrated hydrochloride C17H26ClN·HCl·H2O in the treatment of obesity and that exerts its therapeutic effect by inhibiting the reuptake of norepinephrine, serotonin, and dopamine
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n.
a drug that acts on the central nervous system to suppress the appetite: it inhibits the reuptake of noradrenaline and serotonin. Sibutramine is used in the treatment of obesity; it is prescribed mainly for those with a body mass index of 30 or over who have failed to respond to standard weight-reduction measures. It is administered by mouth; side-effects include dry mouth, constipation, and insomnia. Trade name: Reductil.
Medical dictionary. 2011.