Akademik

1. A condensation product of adenine and d-ribose; a nucleoside found among the hydrolysis products of all nucleic acid s and of the various adenine nucleotides. A. accumulates in severe combined immunodeficiency disease. 2. A potent coronary vasodilator used in place of exercise for radionuclide myocardial perfusion studies. SYN: 9-β-d-ribofuranosyladenine.

- a. cyclic phosphate a. 3′,5′-cyclic monophosphate.

- a. deaminase an enzyme found in mammalian tissues, capable of catalyzing the deamination of a., forming inosine and ammonia. A deficiency of a. deaminase can lead to one form of severe combined immunodeficiency disease.

- a. diphosphate a. 5′-diphosphate.

- a. kinase enzyme catalyzing the transfer of a phosphate group from MgATP to a., forming MgADP and AMP. An important step in nucleoside salvage.

- a. monophosphate (AMP) specifically, a.-5′-monophosphate. See adenylic acid.

- a. nucleosidase an enzyme hydrolyzing a. to adenine and d-ribose.

- a. phosphate specifically, a. 3′- or 5′-phosphate. See adenylic acid.

- a. tetraphosphate a condensation product of a. with tetraphosphoric acid at the 5′ position.

- a. triphosphate SYN: a. 5′-triphosphate.

aden·o·sine ə-'den-ə-.sēn, -sən n a nucleoside C₁₀H₁₃N₅O₄ that is a constituent of RNA yielding adenine and ribose on hydrolysis

a nucleoside that contains adenine and the sugar ribose and occurs in ATP. It is also used as an anti-arrhythmic drug to stop supraventricular tachycardia and restore a normal heart rhythm. As such, it needs to be injected quickly, which may fleetingly make the patient feel faint and develop chest pain. Trade name: Adenocor.