to get angry, annoyed, or upset
Thesaurus: to be, or to become angry or annoyedsynonym
Main entry: knickers
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get your knickers in a twist
Brit informal : to become upset about something that is not very important
Don't get your knickers in a twist: I'll be ready in a minute!
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Main Entry: ↑knickers
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get your knickers in a twist — see ↑knickers
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Main Entry: ↑twist
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get your ˈknickers in a twist idiom
Useful english dictionary. 2012.