A state of immunologic dissimilarity of tissues sufficient to cause rejection of a homograft when tissue is transplanted from one individual to another; implies a difference in histocompatibility genes in donor and recipient.
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his·to·in·com·pat·i·bil·i·ty 'his-(.)tō-.in-kəm-.pat-ə-'bil-ət-ē n, pl -ties a state of mutual intolerance between tissues (as of a fetus and its mother or a graft and its host) that normally leads to reaction against or rejection of one by the other
his·to·in·com·pat·ible -kəm-.pat-ə-bəl adj
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his·to·in·com·pat·i·bil·i·ty (his″to-in″kəm-pat″ĭ-bilґĭ-te) the quality or state of being histoincompatible.Medical dictionary. 2011.