co-tri·mox·a·zole .kō-.trī-'mäk-sə-.zōl n a bactericidal combination of trimethoprim and sulfamethoxazole in the ratio of one to five used esp. for chronic urinary tract infections
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n.
an antibacterial drug consisting of sulfamethoxazole (a sulphonamide) and trimethoprim. Since both these drugs are well absorbed and rapidly excreted - and each potentiates the action of the other - co-trimoxazole is taken by mouth and is particularly useful for treating urinary-tract, respiratory-tract, and gastrointestinal infections. Because of the severity of the side-effects, which are those of the sulphonamide, co-trimoxazole is now less frequently prescribed than formerly. Trade name: Septrin.
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co-tri·mox·a·zole (ko″tri-moksґə-zol) pharmacy equivalent name for a combination of trimethoprim and sulfamethoxazole, an antibacterial and antiprotozoal used in the treatment of pneumocystis pneumonia, bronchitis, otitis media, enterocolitis due to Shigella, urinary tract infections, and traveler's diarrhea; administered orally or intravenously.Medical dictionary. 2011.