1 Med. a change in the physical or mental condition of a person, regarded as evidence of a disease (cf. SIGN 5).
2 a sign of the existence of something.
Etymology: ME synthoma f. med.L sinthoma, & f. LL symptoma f. Gk sumptoma -atos chance, symptom, f. sumpipto happen (as SYN-, pipto fall)
Useful english dictionary. 2012.