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1. A wound or injury. 2. A pathologic change in the tissues. 3. One of the individual points or patches of a multifocal disease. [L. laedo, pp. laesus, to injure]
- Baehr-Lohlein l. SYN: Lohlein-Baehr l..
- Bankart l. a tear of the anterior glenoid labrum accompanying detachment of the inferior glenohumeral ligament.
- benign lymphoepithelial l. benign tumor-like masses of lymphoid tissue in the parotid gland, containing scattered small, mainly solid islands of epithelial cells. SYN: Godwin tumor.
- Bracht-Wächter l. a focal collection of lymphocytes and mononuclear cells within the myocardium in bacterial endocarditis.
- coin l. of lungs SYN: nodular opacity.
- Dieulafoy l. an abnormally large submucosal artery located in the proximal stomach that may be the site of acute and recurrent episodes of massive hemorrhage.
- Duret l. small hemorrhage(s) in the floor of the fourth ventricle or beneath the aqueduct of Sylvius.
- gross l. a l. plainly visible to the naked eye.
- high-grade squamous intraepithelial l. (HSIL, HGSIL) term used in the Bethesda system for reporting cervical/vaginal cytologic diagnosis to describe a spectrum of noninvasive cervical epithelial abnormalities, including moderate and severe dysplasia, carcinoma in situ, and cervical intraepithelial neoplasia grades 2 and 3. SEE ALSO: Bethesda system, ASCUS, atypical glandular cells of undetermined significance, under cell, low-grade squamous intraepithelial l..
- Hill-Sachs l. an irregularity seen in the head of the humerus following anterior dislocation of the shoulder; caused by impaction of posterolateral portion of the head of the humerus against the anterior edge of the glenoid.
- Janeway l. one of the stigmata of infectious endocarditis : irregular, erythematous, flat, painless macules on the palms, soles, thenar and hypothenar eminences of the hands, tips of the fingers, and plantar surfaces of the toes; rarely a diffuse rash. In acute endocarditis the lesions may be hemorrhagic or purple.
- Lohlein-Baehr l. focal embolic glomerulonephritis occurring in bacterial endocarditis. SYN: Baehr-Lohlein l..
- lower motor neuron l. injury to motor cells in the brainstem or spinal cord, or of the axons derived from them.
- low-grade squamous intraepithelial l. (LGSIL, LSIL) term used in the Bethesda system for reporting cervical/vaginal cytologic diagnosis to describe a spectrum of noninvasive cervical epithelial abnormalities; these lesions include the cellular changes associated with human papilloma virus cytopathologic effect and mild dysplasia (cervical intraepithelial neoplasia grade 1). SEE ALSO: Bethesda system, reactive changes, under change, ASCUS, atypical glandular cells of undetermined significance, under cell.
- precancerous l. a noninvasive l. with a predictable likelihood of becoming malignant; e.g., actinic keratosis.
- radial sclerosing l. a variant of sclerosing adenosis of the breast with central scar formation and radiating hyperplastic ducts. SYN: radial scar.
- supranuclear l. injury to cerebral descending (corticonuclear) fibers above the brainstem or spinal motor nerve nucleus. SYN: upper motor neuron l..
- wire-loop l. thickening of the basement membrane, with fibrinoid staining, of scattered peripheral capillaries in renal glomeruli; characteristic of renal involvement in systemic lupus erythematosus; the appearance of an affected capillary wall resembles a loop used in microbiology.
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le·sion 'lē-zhən n an abnormal change in structure of an organ or part due to injury or disease esp one that is circumscribed and well defined
le·sioned -zhənd adj
lesion vt to produce lesions in (as an animal's brain)
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n.
a zone of tissue with impaired function as a result of damage by disease or wounding. Apart from direct physical injury, examples of primary lesions include abscesses, ulcers, and tumours; secondary lesions (such as crusts and scars) are derived from primary ones.
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le·sion (leґzhən) [L. laesio; laedere to hurt] any pathological or traumatic discontinuity of tissue or loss of function of a part.Medical dictionary. 2011.